#193: My Life Extension Pilgrimage to Easter Island

This episode was a blast.

It was a tropical exploration of biology, life extension, and all good things. This included a lot of Carmenere wine and good old-fashioned ball busting.

I was joined by:

Peter Attia, MD (@peterattiamd), who rejoins the show (catch his last appearance here). He is a former ultra-endurance athlete (e.g., swimming 25-mile races), compulsive self-experimenter, and one of the most fascinating human beings I know. He is one of my go-to doctors for anything performance- or longevity-related. Peter earned his MD from Stanford University and holds a BSc in mechanical engineering and applied mathematics from Queen's University in Kingston, Ontario. He did his residency in general surgery at the Johns Hopkins Hospital, and conducted research at the National Cancer Institute under Dr. Steven Rosenberg, where Peter focused on the role of regulatory T cells in cancer regression and other immune-based therapies for cancer.

David M. Sabatini, M.D., Ph.D. (@DMSabatini) of MIT's Whitehead Institute for Biomedical Research. David is on a short list for the Nobel Prize for his work in elucidating the role of rapamycin and mTOR.

Navdeep S. Chandel, Ph.D., the David W. Cugell Professor of Medicine and Cell Biology at the Feinberg School of Medicine, Northwestern University. Nav established his lab there to further the understanding of how mitochondria work as signaling organelles to regulate physiology and pathology. He is also the author of Navigating Metabolism.

Perhaps you've heard of people in Silicon Valley taking metformin, rapamycin, and supplements for longevity. In this conversation, we dig into the real science, what current evidence supports (or doesn't), and other important matters like how to staple properly, which fonts reasonable people use, and why Borat is a genius. Enjoy!

Show notes and links for this episode can be found at www.fourhourworkweek.com/podcast.

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